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adjective

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tragic - Something very sad often involving suffering.

The story of how Oedipus mistakenly killed his father and married his mother is a tragic story.

noun

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inflammation - A physical condition characterized by redness, heat, swelling, and pain, often as a response to injury or infection.

The redness of the big toe was caused by an infection, and the inflammation was visible and painful.

adjective

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excruciating - Intensely painful

Becky had to see the dentist because her toothache was causing her excruciating pain.

noun

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shackles - A device, such as a chain or cuff, designed to physically limit or control a person or thing's movement.

Shackles were placed on the prisoner's feet so that he would not be able to run away and escape.

adjective

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impoverished - Very poor.

We can hardly imagine how impoverished the average person was during the Middle Ages.

verb

See noun

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torment - Cause to experience severe mental or physical suffering

William enjoyed tormenting his younger sister until she would run away and complain to their mother.

noun

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throes - Intense or violent pain and struggle, especially accompanying birth, death, or great change

Samantha experienced agonizing pain during the throes of childbirth.

adjective

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agonizing - Something that causes great physical or mental pain.

After she took the final exam, it was agonizing to her that for a whole week she wouldn't find out the results.

noun

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angst - A feeling of deep anxiety or dread, typically an unfocused one about the human condition or the state of the world in general

Edvard Munch's famous painting, "The Scream," is often viewed as an expression of angst in an uncertain world.

adjective

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grueling - Extremely tiring and demanding

Troops go through grueling training before they can finally serve their country.

noun

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plight - A difficult or unfortunate situation, often one that involves hardship or adversity.

The community came together to help improve the plight of the homeless during the harsh winter months.

adjective

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afflicted - Suffering from a serious problem, illness, or pain, be it mental or physical.

Many people are afflicted with anxiety in high-pressure situations.