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affliction - Something that causes pain or suffering.

When Pharoah didn't let the people go, Moses gave Egypt one affliction after another.

adjective

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exasperating - Intensely irritating; infuriating

Molly tried to enter the information in the online form, but she found the confusing directions so exasperating that she grabbed her own hair and screamed in frustration.

adjective

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grueling - Extremely tiring and demanding

Troops go through grueling training before they can finally serve their country.

noun

See verb

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exile - The state of being banned or forced to live away from one's native country, often for political reasons.

After the revolution, the king lived in exile in a foreign land.

verb

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wince - To give a slight involuntary grimace or shrinking movement of the body out of or in anticipation of pain or distress

Tiger winced as he realized he had hit the ball too far beyond the hole.

adjective

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excruciating - Intensely painful

Becky had to see the dentist because her toothache was causing her excruciating pain.

noun

See verb

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torment - Severe physical or mental suffering

Sufferers of depression must deal with the torment of their own thoughts on a regular basis.

adjective

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traumatic - Causing severe and lasting emotional shock and pain.

Bill survived the hurricane at sea on his fishing boat, but it took years for him to recover emotionally from the traumatic experience.

noun

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shackles - A device, such as a chain or cuff, designed to physically limit or control a person or thing's movement.

Shackles were placed on the prisoner's feet so that he would not be able to run away and escape.

noun

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ordeal - A painful or horrific experience, especially a protracted one

Knowing it was a fight to the death, the gladiator realized that this was an ordeal he would have to overcome if he wanted to survive.

noun

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pang - A sudden sharp pain or painful emotion

The year was 1900, and Dmitri felt a pang of nostalgia and regret as he boarded the boat for America, knowing that he would probably never see his 'old world' again.

noun

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plight - A difficult or unfortunate situation, often one that involves hardship or adversity.

The community came together to help improve the plight of the homeless during the harsh winter months.