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wince - To give a slight involuntary grimace or shrinking movement of the body out of or in anticipation of pain or distress

Tiger winced as he realized he had hit the ball too far beyond the hole.

verb

See noun

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plague - To cause constant worry, annoyance, or distress, often by repeatedly confronting someone with problems or challenges.

She was plagued by constant headaches, making it hard for her to focus on her work.

noun

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plight - A difficult or unfortunate situation, often one that involves hardship or adversity.

The community came together to help improve the plight of the homeless during the harsh winter months.

verb

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writhe - To make continual twisting, squirming movements or contortions of the body

The soccer player writhed in pain on the ground after spraining his ankle.

adjective

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exasperating - Intensely irritating; infuriating

Molly tried to enter the information in the online form, but she found the confusing directions so exasperating that she grabbed her own hair and screamed in frustration.

noun

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angst - A feeling of deep anxiety or dread, typically an unfocused one about the human condition or the state of the world in general

Edvard Munch's famous painting, "The Scream," is often viewed as an expression of angst in an uncertain world.

noun

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shackles - A device, such as a chain or cuff, designed to physically limit or control a person or thing's movement.

Shackles were placed on the prisoner's feet so that he would not be able to run away and escape.

adjective

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afflicted - Suffering from a serious problem, illness, or pain, be it mental or physical.

Many people are afflicted with anxiety in high-pressure situations.

noun

See verb

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burden - something you carry or withstand with much difficulty.

Financial debt can be a huge burden on families.

adjective

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humiliated - To feel ashamed after someone embarrasses you in front of others.

When Jim revealed to everyone at the party that Marty hadn't even finished 6th grade, Marty felt humiliated.

adjective

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impoverished - Very poor.

We can hardly imagine how impoverished the average person was during the Middle Ages.

noun

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throes - Intense or violent pain and struggle, especially accompanying birth, death, or great change

Samantha experienced agonizing pain during the throes of childbirth.