berserk -
To behave in a wild and uncontrolled way as a result of something unexpected happening.
When Anne found out that she had lost all her money as a result of stock fraud, she went berserk, running around the house, screaming and breaking dishes.
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daffy -
Silly, different, strange, and funny
Fred had a twirled mustache and wore an oddly colored suit, but the town's residents simply viewed him as daffy instead of someone to be afraid of.
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megalomaniac -
Someone who has an unnaturally strong wish for power and control.
The dictator showed signs of being a megalomaniac even as a child, the way he bossed everyone around in the schoolyard.
noun
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crackpot -
A slightly strange or foolish person
Wearing mismatched clothing and yelling to nobody in particular, the crackpot was amusing and ignored by the people who passed him by.
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hysterical -
Having uncontrolled extreme emotion
When Amy found out that her house had been destroyed by the tornado, she broke down into hysterical crying, and could not be comforted for hours.
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delirious -
In a disturbed state of mind, often due to illness or fever, leading to confusion and hallucinations.
After three sleepless nights, he was delirious and barely able to speak clearly.
noun
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weirdo -
A person whose dress or behavior seems strange
The weirdo kept peeking at everyone from behind the bushes.
adjective
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batty -
Mad and slightly crazy, usually in a humorous way
The computer system wouldn't let Greg log on or change his password, and it was driving him batty.
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cantankerous -
Bad-tempered, argumentative, and uncooperative
The constant arguing of the cantankerous couple living above Ann always kept her up at night.
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catatonic -
Appearing to be in a daze or stupor; unresponsive, not moving or reacting.
His experiment with psychodelics left him in a catatonic state where he showed almost no emotion, and it that took years for him to recover.
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lunatic -
A person who is crazy
Martha was a defensive driver, to be safer with regards to a possible lunatic behind the wheel of another car.
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nuts -
Crazy, insane, or stupid, often in a humorous way
Bill's friends thought he was nuts for swimming in the middle of the winter.