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crackpot - A slightly strange or foolish person

Wearing mismatched clothing and yelling to nobody in particular, the crackpot was amusing and ignored by the people who passed him by.

adjective

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deranged - Behaving in an uncontrolled or dangerous way because of mental illness

Charles Manson led a group of followers who became mentally deranged as a result of taking too many psychedelic drugs

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psycho - A person with severe mental health issues, often describing someone who behaves in an erratic or dangerous manner.

She accused him of being a psycho and told him to leave after he repeatedly showed up uninvited and acted innappropriately.

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unhinged - Mentally unbalanced and unstable

Trevor crossed the street when he saw the unhinged person yelling at him.

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hysterical - Having uncontrolled extreme emotion

When Amy found out that her house had been destroyed by the tornado, she broke down into hysterical crying, and could not be comforted for hours.

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lunatic - A person who is crazy

Martha was a defensive driver, to be safer with regards to a possible lunatic behind the wheel of another car.

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daffy - Silly, different, strange, and funny

Fred had a twirled mustache and wore an oddly colored suit, but the town's residents simply viewed him as daffy instead of someone to be afraid of.

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loony - Crazy or silly

The patients in the mental hospital could be described as loony, but the doctors tried to treat them as normal human beings with normal problems in order to try to help them get better.

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lunacy - Stupid or crazy ideas or behavior that is likely to have bad results

When Edwin Hubble suggested in 1922 that most of the little dots in the sky are entire galaxies, most scientists thought that the idea was sheer lunacy.

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maniac - Someone who is mentally ill tending towards violent and dangerous behavior.

The film’s villain was portrayed as a ruthless maniac with no regard for human life.

adjective

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delusional - Seeing or believing things that are not real

Betty was confident that she would be a millionaire by the time she would be 25, but her friends thought she was delusional.

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delirious - In a disturbed state of mind, often due to illness or fever, leading to confusion and hallucinations.

After three sleepless nights, he was delirious and barely able to speak clearly.