deranged -
Behaving in an uncontrolled or dangerous way because of mental illness
Charles Manson led a group of followers who became mentally deranged as a result of taking too many psychedelic drugs
adjective
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batty -
Mad and slightly crazy, usually in a humorous way
The computer system wouldn't let Greg log on or change his password, and it was driving him batty.
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lunacy -
Stupid or crazy ideas or behavior that is likely to have bad results
When Edwin Hubble suggested in 1922 that most of the little dots in the sky are entire galaxies, most scientists thought that the idea was sheer lunacy.
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catatonic -
Appearing to be in a daze or stupor; unresponsive, not moving or reacting.
His experiment with psychodelics left him in a catatonic state where he showed almost no emotion, and it that took years for him to recover.
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crank -
Someone who others think has unusual ideas or behaves strangely
Bill was seen as crank by his friends, because of the way he always spoke of the dangers of eating meat and being vaccinated.
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nuts -
Crazy, insane, or stupid, often in a humorous way
Bill's friends thought he was nuts for swimming in the middle of the winter.
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megalomaniac -
Someone who has an unnaturally strong wish for power and control.
The dictator showed signs of being a megalomaniac even as a child, the way he bossed everyone around in the schoolyard.
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lunatic -
A person who is crazy
Martha was a defensive driver, to be safer with regards to a possible lunatic behind the wheel of another car.
adjective
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zany -
Amusingly unconventional and different
Einstein was unique among geniuses in that he also had a silly and zany side of his personality.
adjective
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daffy -
Silly, different, strange, and funny
Fred had a twirled mustache and wore an oddly colored suit, but the town's residents simply viewed him as daffy instead of someone to be afraid of.
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maniac -
Someone who is mentally ill tending towards violent and dangerous behavior.
The film’s villain was portrayed as a ruthless maniac with no regard for human life.
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kooky -
Strange and different, in a funny way
Salvador Dali's kooky appearance was only exceeded by his even more bizarre paintings.
