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Arduous - Physically or mentally challenging and difficult.

Training for the marathon was arduous, but he never gave up, and in the end he doing very well.

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Hangover - A set of unpleasant physical effects following heavy alcohol consumption, such as headache, nausea, and fatigue.

He spent the whole morning in bed, recovering from a bad hangover after a night of drinking.

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squeamish - (of a person) easily made to feel sick, faint, or disgusted, especially by unpleasant images, such as the sight of blood

Nico was so squeamish about receiving a flu shot that he broke out into a sweat.

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harried - To be busy and annoyed by the demands of others

Jim didn't like being a waiter, because he always felt harried by the demands of all the customers.

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grimace - An ugly, twisted expression on a person's face, typically expressing disgust, pain, or wry amusement

Rowan made a grimace when he saw the disgusting plate of food given to him.

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skittish - (of an animal, especially of a horse) excitable or easily scared

Bill's horse was especially skittish around people it didn't know, so they had to be careful when Bill's friend Fred wanted to stroke the horse's mane.

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Hideout - A secret place where someone can hide from others, especially from the law.

The thieves retreated to their hideout after the robbery.

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leery - Cautious or wary due to realistic suspicions

Ever since she was bitten by a pitbull, Grace was leery of any dog she encountered.

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queasy - Nauseated; feeling sick

Kevin felt queasy after eating sushi he bought at the gas station.

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Achy - Experiencing a dull, persistent pain in the body, often due to illness or tiredness.

The construction worker's achy muscles were a sign that he needed a vacation.

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grimace - To make an an ugly, twisted expression on a person's face, typically expressing disgust, pain, or wry amusement

The soccer player grimaced as he fell to the ground in pain.

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sweltering - Uncomfortably hot

In India during the summer, the sweltering heat literally melted the roads.