adjective
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agonizing - Something that causes great physical or mental pain.
noun
See verb
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burden - something you carry or withstand with much difficulty.
verb
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flinch - To make a quick, nervous movement of the face or body as an instinctive reaction to surprise, fear or pain
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wince - To give a slight involuntary grimace or shrinking movement of the body out of or in anticipation of pain or distress
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hardship - Severe suffering or difficulty caused by lack of necessities like food, money, or shelter.
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ordeal - A painful or horrific experience, especially a protracted one
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plight - A difficult or unfortunate situation, often one that involves hardship or adversity.
See noun
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torment - Cause to experience severe mental or physical suffering
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standstill - A halt in activity, usually temporary but total.
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strenuous - Requiring great effort, energy, or strength, needing vigorous or intense in activity or action.
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bruise - To hurt someone emotionally or physically, leaving a lasting feeling of pain or vulnerability.
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plague - To cause constant worry, annoyance, or distress, often by repeatedly confronting someone with problems or challenges.