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wince - To give a slight involuntary grimace or shrinking movement of the body out of or in anticipation of pain or distress

Tiger winced as he realized he had hit the ball too far beyond the hole.

adjective

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grueling - Extremely tiring and demanding

Troops go through grueling training before they can finally serve their country.

verb

See noun

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torment - Cause to experience severe mental or physical suffering

William enjoyed tormenting his younger sister until she would run away and complain to their mother.

noun

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standstill - A halt in activity, usually temporary but total.

Traffic came to a standstill after the accident on the highway.

adjective

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impoverished - Very poor.

We can hardly imagine how impoverished the average person was during the Middle Ages.

adjective

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afflicted - Suffering from a serious problem, illness, or pain, be it mental or physical.

Many people are afflicted with anxiety in high-pressure situations.

verb

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flinch - To make a quick, nervous movement of the face or body as an instinctive reaction to surprise, fear or pain

Debbie was very brave and didn’t flinch when the nurse put the needle in her arm to give her the flu shot.

noun

See verb

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torment - Severe physical or mental suffering

Sufferers of depression must deal with the torment of their own thoughts on a regular basis.

noun

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shackles - A device, such as a chain or cuff, designed to physically limit or control a person or thing's movement.

Shackles were placed on the prisoner's feet so that he would not be able to run away and escape.

noun

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affliction - Something that causes pain or suffering.

When Pharoah didn't let the people go, Moses gave Egypt one affliction after another.

noun

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anguish - Severe mental or physical pain or suffering

With her personal and professional life in disarray, Jenny's anguish was often too much for her to bear.

verb

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degenerate - To decline or deteriorate physically, mentally, or morally

After Bill started taking drugs, his life went downhill until his his relationships, health, and finances had totally degenerated.