anguish -
Severe mental or physical pain or suffering
With her personal and professional life in disarray, Jenny's anguish was often too much for her to bear.
noun
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pang -
A sudden sharp pain or painful emotion
The year was 1900, and Dmitri felt a pang of nostalgia and regret as he boarded the boat for America, knowing that he would probably never see his 'old world' again.
adjective
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strenuous -
Requiring great effort, energy, or strength, needing vigorous or intense in activity or action.
Hiking up the mountain was a strenuous task, but the view was worth it.
noun
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plight -
A difficult or unfortunate situation, often one that involves hardship or adversity.
The community came together to help improve the plight of the homeless during the harsh winter months.
verb
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plague -
To cause constant worry, annoyance, or distress, often by repeatedly confronting someone with problems or challenges.
She was plagued by constant headaches, making it hard for her to focus on her work.
noun
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throes -
Intense or violent pain and struggle, especially accompanying birth, death, or great change
Samantha experienced agonizing pain during the throes of childbirth.
noun
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shackles -
A device, such as a chain or cuff, designed to physically limit or control a person or thing's movement.
Shackles were placed on the prisoner's feet so that he would not be able to run away and escape.
verb
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degenerate -
To decline or deteriorate physically, mentally, or morally
After Bill started taking drugs, his life went downhill until his his relationships, health, and finances had totally degenerated.
noun
See verb
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exile -
The state of being banned or forced to live away from one's native country, often for political reasons.
After the revolution, the king lived in exile in a foreign land.
verb
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torment -
Cause to experience severe mental or physical suffering
William enjoyed tormenting his younger sister until she would run away and complain to their mother.
verb
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flinch -
To make a quick, nervous movement of the face or body as an instinctive reaction to surprise, fear or pain
Debbie was very brave and didn’t flinch when the nurse put the needle in her arm to give her the flu shot.
noun
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standstill -
A halt in activity, usually temporary but total.
Traffic came to a standstill after the accident on the highway.