anguish -
Severe mental or physical pain or suffering
With her personal and professional life in disarray, Jenny's anguish was often too much for her to bear.
adjective
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tragic -
Something very sad often involving suffering.
The story of how Oedipus mistakenly killed his father and married his mother is a tragic story.
verb
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bruise -
To hurt someone emotionally or physically, leaving a lasting feeling of pain or vulnerability.
The teacher's harsh words bruised his self-esteem.
adjective
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exasperating -
Intensely irritating; infuriating
Molly tried to enter the information in the online form, but she found the confusing directions so exasperating that she grabbed her own hair and screamed in frustration.
verb
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writhe -
To make continual twisting, squirming movements or contortions of the body
The soccer player writhed in pain on the ground after spraining his ankle.
noun
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shackles -
A device, such as a chain or cuff, designed to physically limit or control a person or thing's movement.
Shackles were placed on the prisoner's feet so that he would not be able to run away and escape.
noun
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cramps -
A painful, involuntary contraction of muscles
When Sharon got cramps in her stomach after eating the fish, she suspected that it may have been spoiled.
noun
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torment -
Severe physical or mental suffering
Sufferers of depression must deal with the torment of their own thoughts on a regular basis.
adjective
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afflicted -
Suffering from a serious problem, illness, or pain, be it mental or physical.
Many people are afflicted with anxiety in high-pressure situations.
noun
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burden -
something you carry or withstand with much difficulty.
Financial debt can be a huge burden on families.
noun
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angst -
A feeling of deep anxiety or dread, typically an unfocused one about the human condition or the state of the world in general
Edvard Munch's famous painting, "The Scream," is often viewed as an expression of angst in an uncertain world.
noun
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pang -
A sudden sharp pain or painful emotion
The year was 1900, and Dmitri felt a pang of nostalgia and regret as he boarded the boat for America, knowing that he would probably never see his 'old world' again.
