angst -
A feeling of deep anxiety or dread, typically an unfocused one about the human condition or the state of the world in general
Edvard Munch's famous painting, "The Scream," is often viewed as an expression of angst in an uncertain world.
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Pain
noun
pang -
A sudden sharp pain or painful emotion
The year was 1900, and Dmitri felt a pang of nostalgia and regret as he boarded the boat for America, knowing that he would probably never see his 'old world' again.
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Pain
noun
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agony -
Extreme physical or mental suffering
Max was in physical agony as he rode his bicycle up the long mountain trail, but spiritually and emotionally he was in heaven.
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Pain
adjective
tragic -
Something very sad often involving suffering.
The story of how Oedipus mistakenly killed his father and married his mother is a tragic story.
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Pain
noun
cramps -
A painful, involuntary contraction of muscles
When Sharon got cramps in her stomach after eating the fish, she suspected that it may have been spoiled.
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Pain
nounverb noun
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Burden -
something you carry or withstand with much difficulty.
Financial debt can be a huge burden on families.
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Pain
noun
throes -
Intense or violent pain and struggle, especially accompanying birth, death, or great change
Samantha experienced agonizing pain during the throes of childbirth.
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Pain
adjective
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Afflicted -
Suffering from a serious problem, illness, or pain, be it mental or physical.
Many people are afflicted with anxiety in high-pressure situations.
