compulsion -
A strong, irresistible urge to do something, often against one's better judgement.
His gambling problem stemmed from a deep psychological compulsion.
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bonkers -
Mentally unbalanced, mad and crazy, usually meant humorously
There were many long stretches of time that Joan was cooped up in the house with her kids, and it was making her go bonkers.
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catatonic -
Appearing to be in a daze or stupor; unresponsive, not moving or reacting.
His experiment with psychodelics left him in a catatonic state where he showed almost no emotion, and it that took years for him to recover.
noun
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crackpot -
A slightly strange or foolish person
Wearing mismatched clothing and yelling to nobody in particular, the crackpot was amusing and ignored by the people who passed him by.
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batty -
Mad and slightly crazy, usually in a humorous way
The computer system wouldn't let Greg log on or change his password, and it was driving him batty.
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daffy -
Silly, different, strange, and funny
Fred had a twirled mustache and wore an oddly colored suit, but the town's residents simply viewed him as daffy instead of someone to be afraid of.
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maniac -
Someone who is mentally ill tending towards violent and dangerous behavior.
The film’s villain was portrayed as a ruthless maniac with no regard for human life.
adjective
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berserk -
To behave in a wild and uncontrolled way as a result of something unexpected happening.
When Anne found out that she had lost all her money as a result of stock fraud, she went berserk, running around the house, screaming and breaking dishes.
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nuts -
Crazy, insane, or stupid, often in a humorous way
Bill's friends thought he was nuts for swimming in the middle of the winter.
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zany -
Amusingly unconventional and different
Einstein was unique among geniuses in that he also had a silly and zany side of his personality.
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lunatic -
A person who is crazy
Martha was a defensive driver, to be safer with regards to a possible lunatic behind the wheel of another car.
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delusional -
Seeing or believing things that are not real
Betty was confident that she would be a millionaire by the time she would be 25, but her friends thought she was delusional.