Loudmouth -
Someone who speaks loudly and without thinking, often causing trouble or embarrassment.
He was a real loudmouth, always bragging about his achievements and never listening to others.
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unhinged -
Mentally unbalanced and unstable
Trevor crossed the street when he saw the unhinged person yelling at him.
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batty -
Mad and slightly crazy, usually in a humorous way
The computer system wouldn't let Greg log on or change his password, and it was driving him batty.
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noun
crackpot -
A slightly strange or foolish person
Wearing mismatched clothing and yelling to nobody in particular, the crackpot was amusing and ignored by the people who passed him by.
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Blabbermouth -
An overly talkative person who speaks without thinking.
Don't tell Jerry things you don't want others to know about, because you can’t trust a blabbermouth with secrets.
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loony -
Crazy or silly
The patients in the mental hospital could be described as loony, but the doctors tried to treat them as normal human beings with normal problems in order to try to help them get better.
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bonkers -
Mentally unbalanced, mad and crazy, usually meant humorously
There were many long stretches of time that Joan was cooped up in the house with her kids, and it was making her go bonkers.
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zany -
Amusingly unconventional and different
Einstein was unique among geniuses in that he also had a silly and zany side of his personality.
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hysterical -
Having uncontrolled extreme emotion
When Amy found out that her house had been destroyed by the tornado, she broke down into hysterical crying, and could not be comforted for hours.
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mercurial -
Changing emotions suddenly and often
Fred loved almost everything about his wife except her mercurial behavior, where her moods changed suddenly between sadness and happiness, or love and anger
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Compulsion -
A strong, irresistible urge to do something, often against one's better judgement.
His gambling problem stemmed from a deep psychological compulsion.
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delusional -
Seeing or believing things that are not real
Betty was confident that she would be a millionaire by the time she would be 25, but her friends thought she was delusional.