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disconcerting - Making someone feel uncertain, uncomfortable or worried

Linda had a disconcerting habit of speaking before thinking about what she should say.

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aggravating - Causing annoyance, irritation, and frustraton by repeated annoying behavior.

It’s so aggravating when people talk loudly during a movie.

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uneasy - Feeling anxious, worried, or uncomfortable about something; feeling a sense of discomfort or restlessness.

She felt uneasy walking alone through the dark alley.

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stiff - Difficult to move one's body, often due to tightness or soreness; rigid or not easily bent; firm in structure.

The new shoes were stiff and uncomfortable at first.

verb

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bristle - (of hair or fur) To stand upright away from the skin, especially in anger or fear

In the darkness lit by only the moon, Warren's hair bristled at the creepy sounds around him.

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skittish - (of an animal, especially of a horse) excitable or easily scared

Bill's horse was especially skittish around people it didn't know, so they had to be careful when Bill's friend Fred wanted to stroke the horse's mane.

verb

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fidget - To make small movements, especially of the hands and feet, through nervousness or impatience

Ron nervously fidgeted with his hands before giving the speech to 10,000 people.

noun

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hangover - A set of unpleasant physical effects following heavy alcohol consumption, such as headache, nausea, and fatigue.

He spent the whole morning in bed, recovering from a bad hangover after a night of drinking.

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swollen - Enlarged beyond normal size, often due to injury, infection, or inflammation.

Her eyes were swollen from crying all night.

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queasy - Feeling nervous, uneasy, or anxious.

After the stock he bougtht kept going down, he felt queasy and thought perhaps he had made a bad decision.

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harried - To be busy and annoyed by the demands of others

Jim didn't like being a waiter, because he always felt harried by the demands of all the customers.

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arduous - Physically or mentally challenging and difficult.

Training for the marathon was arduous, but he never gave up, and in the end he doing very well.