ordeal -
A painful or horrific experience, especially a protracted one
Knowing it was a fight to the death, the gladiator realized that this was an ordeal he would have to overcome if he wanted to survive.
adjective
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afflicted -
Suffering from a serious problem, illness, or pain, be it mental or physical.
Many people are afflicted with anxiety in high-pressure situations.
verb
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writhe -
To make continual twisting, squirming movements or contortions of the body
The soccer player writhed in pain on the ground after spraining his ankle.
noun
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pang -
A sudden sharp pain or painful emotion
The year was 1900, and Dmitri felt a pang of nostalgia and regret as he boarded the boat for America, knowing that he would probably never see his 'old world' again.
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throes -
Intense or violent pain and struggle, especially accompanying birth, death, or great change
Samantha experienced agonizing pain during the throes of childbirth.
noun
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affliction -
Something that causes pain or suffering.
When Pharoah didn't let the people go, Moses gave Egypt one affliction after another.
noun
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hardship -
Severe suffering or difficulty caused by lack of necessities like food, money, or shelter.
Many families are facing economic hardship due to rising living costs.
noun
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torment -
Severe physical or mental suffering
Sufferers of depression must deal with the torment of their own thoughts on a regular basis.
noun
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burden -
something you carry or withstand with much difficulty.
Financial debt can be a huge burden on families.
verb
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flinch -
To make a quick, nervous movement of the face or body as an instinctive reaction to surprise, fear or pain
Debbie was very brave and didn’t flinch when the nurse put the needle in her arm to give her the flu shot.
adjective
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excruciating -
Intensely painful
Becky had to see the dentist because her toothache was causing her excruciating pain.
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tragic -
Something very sad often involving suffering.
The story of how Oedipus mistakenly killed his father and married his mother is a tragic story.