writhe -
To make continual twisting, squirming movements or contortions of the body
The soccer player writhed in pain on the ground after spraining his ankle.
verb
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torment -
Cause to experience severe mental or physical suffering
William enjoyed tormenting his younger sister until she would run away and complain to their mother.
noun
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anguish -
Severe mental or physical pain or suffering
With her personal and professional life in disarray, Jenny's anguish was often too much for her to bear.
noun
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angst -
A feeling of deep anxiety or dread, typically an unfocused one about the human condition or the state of the world in general
Edvard Munch's famous painting, "The Scream," is often viewed as an expression of angst in an uncertain world.
verb
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degenerate -
To decline or deteriorate physically, mentally, or morally
After Bill started taking drugs, his life went downhill until his his relationships, health, and finances had totally degenerated.
adjective
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afflicted -
Suffering from a serious problem, illness, or pain, be it mental or physical.
Many people are afflicted with anxiety in high-pressure situations.
adjective
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exasperating -
Intensely irritating; infuriating
Molly tried to enter the information in the online form, but she found the confusing directions so exasperating that she grabbed her own hair and screamed in frustration.
noun
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torment -
Severe physical or mental suffering
Sufferers of depression must deal with the torment of their own thoughts on a regular basis.
verb
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flinch -
To make a quick, nervous movement of the face or body as an instinctive reaction to surprise, fear or pain
Debbie was very brave and didn’t flinch when the nurse put the needle in her arm to give her the flu shot.
adjective
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strenuous -
Requiring great effort, energy, or strength, needing vigorous or intense in activity or action.
Hiking up the mountain was a strenuous task, but the view was worth it.
noun
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standstill -
A halt in activity, usually temporary but total.
Traffic came to a standstill after the accident on the highway.
adjective
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grueling -
Extremely tiring and demanding
Troops go through grueling training before they can finally serve their country.