adjective
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intolerable - Causing great discomfort or distress; too extreme or severe to be endured;
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taboo - A subject, word, or action that is avoided for religious or social reasons
noun
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catastrophe - An event causing great and often sudden damage or suffering; a disaster
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adversity - A difficult situation or time in one's life
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abysmal - A deplorable, poor or inferior state.
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diabolical - Extremely evil or cruel; wicked.
verb
See noun
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disgrace - To make people stop respecting you by doing something very bad
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debris - Broken or torn pieces of something larger
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purgatory - An extremely unpleasant place or experience that causes suffering
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blight - A plant disease, especially one caused by fungi such as mildews, rusts, and smuts
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calamity - An event causing great and often sudden damage or distress; a disaster.
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slum - A very poor and crowded area, especially of a city