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agony - Extreme physical or mental suffering

Max was in physical agony as he rode his bicycle up the long mountain trail, but spiritually and emotionally he was in heaven.

noun

See verb

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torment - Severe physical or mental suffering

Sufferers of depression must deal with the torment of their own thoughts on a regular basis.

adjective

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grueling - Extremely tiring and demanding

Troops go through grueling training before they can finally serve their country.

noun

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throes - Intense or violent pain and struggle, especially accompanying birth, death, or great change

Samantha experienced agonizing pain during the throes of childbirth.

noun

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anguish - Severe mental or physical pain or suffering

With her personal and professional life in disarray, Jenny's anguish was often too much for her to bear.

adjective

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exasperating - Intensely irritating; infuriating

Molly tried to enter the information in the online form, but she found the confusing directions so exasperating that she grabbed her own hair and screamed in frustration.

verb

See noun

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plague - To cause constant worry, annoyance, or distress, often by repeatedly confronting someone with problems or challenges.

She was plagued by constant headaches, making it hard for her to focus on her work.

noun

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shackles - A device, such as a chain or cuff, designed to physically limit or control a person or thing's movement.

Shackles were placed on the prisoner's feet so that he would not be able to run away and escape.

verb

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flinch - To make a quick, nervous movement of the face or body as an instinctive reaction to surprise, fear or pain

Debbie was very brave and didn’t flinch when the nurse put the needle in her arm to give her the flu shot.

noun

See verb

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burden - something you carry or withstand with much difficulty.

Financial debt can be a huge burden on families.

noun

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cramps - A painful, involuntary contraction of muscles

When Sharon got cramps in her stomach after eating the fish, she suspected that it may have been spoiled.

noun

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trauma - A deeply distressing or disturbing experience, especially one with lasting emotional impact; a psychological or emotional wound, often resulting from an intense or life-threatening event.

Childhood trauma can have long-lasting effects on a person’s mental health